Article
Single nucleotide polymorphisms associated with metastatic tumour antigen 1 overexpression in patients with hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2012
Lee Sae Hwan, Chung Young-Hwa, Kim Jeong A, Lee Danbi, Jin Young-Joo, Shim Ju Hyun, Jang Myoung-Kuk, Cho Eun-Young, Shin Eun-Soon, Lee Jong-Eun, Park Neung Hwa, Yu Eunsil, Lee Young Joo
Abstract excerpt
BACKGROUNDS/AIMS: Metastatic tumour antigen 1 (MTA1) promotes angiogenesis by stabilizing hypoxia-inducible factor-1α (HIF-1α), which is closely associated with frequent postoperative recurrence and poor survival in patients with HCC. In this study, we determined single nucleotide polymorphisms (SNPs) in angiogenesis-related genes that are associated with MTA1 overexpression in HCC tissues. METHODS: A total of...
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