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Article

Different polymorphisms in HIF-1α may exhibit different effects on cancer risk in Asians: evidence from nearly forty thousand participants.

Aging - 4 Nov 2020

Liu Yichen, Zhu Xiaoqi, Zhou Xiaoyi, Cheng Jingwen, Fu Xiaoyu, Xu Jingsheng, Wang Yuya, Zhong Yueping, Chu Minjie

Abstract excerpt

The effect of different SNPs in HIF-1α and cancer susceptibility remain indistinct. Here, we evaluated the association between all identified SNPs (rs11549465, rs11549467 and rs2057482) in HIF-1α and the overall risk of cancer in all case-control studies published before April 2020. A total of 54 articles including 56 case-control studies were included in this analysis. We found that variant genotypes of...

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PMID: 33154192
DOI: 10.18632/aging.103871
PMCID: PMC7695358

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