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Article

Malthusian Parameters as Estimators of the Fitness of Microbes: A Cautionary Tale about the Low Side of High Throughput.

PloS one - 1 Jan 2015

Concepción-Acevedo Jeniffer, Weiss Howard N, Chaudhry Waqas Nasir, Levin Bruce R

Abstract excerpt

The maximum exponential growth rate, the Malthusian parameter (MP), is commonly used as a measure of fitness in experimental studies of adaptive evolution and of the effects of antibiotic resistance and other genes on the fitness of planktonic microbes. Thanks to automated, multi-well optical density plate readers and computers, with little hands-on effort investigators can readily obtain hundreds of estimates of...

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Identifiers

PMID: 26114477
DOI: 10.1371/journal.pone.0126915
PMCID: PMC4482697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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