Article
The phenotype-fitness map in experimental evolution of phages.
PloS one - 1 Jan 2011
Bull James J, Heineman Richard H, Wilke Claus O
Abstract excerpt
Evolutionary biologists commonly interpret adaptations of organisms by reference to a phenotype-fitness map, a model of how different states of a phenotype affect fitness. Notwithstanding the popularity of this approach, it remains difficult to directly test these mappings, both because the map often describes only a small subset of phenotypes contributing to total fitness and because direct measures of fitness...
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