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Article

Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy.

Journal of applied physiology (Bethesda, Md. : 1985) - 15 Aug 2015

Dupré-Aucouturier Sylvie, Castells Josiane, Freyssenet Damien, Desplanches Dominique

Abstract excerpt

Skeletal muscle atrophy is commonly associated with immobilization, ageing, and catabolic diseases such as diabetes and cancer cachexia. Epigenetic regulation of gene expression resulting from chromatin remodeling through histone acetylation has been implicated in muscle disuse. The present work...

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Source

Identifiers

PMID: 26112243
DOI: 10.1152/japplphysiol.01031.2014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26112243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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