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Article

Skeletal muscle growth defect in human growth hormone transgenic rat is accompanied by phenotypic changes in progenitor cells.

Age (Dordrecht, Netherlands) - 1 Jun 2010

Shibata Shingo, Ueno Chiori, Ito Tsuyoshi, Yamanouchi Keitaro, Matsuwaki Takashi, Nishihara Masugi

Abstract excerpt

Growth hormone (GH) is known to have a pivotal role in the maintenance of skeletal muscle mass. Sarcopenia, the loss of skeletal muscle mass, is a common phenomenon in aging, and it is widely accepted that sarcopenia is largely attributed to age-related decline in GH secretion. In the present study, we tested if human growth hormone transgenic rats (GH-TG rats) whose plasma GH levels are maintained relatively low...

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Identifiers

PMID: 20431991
DOI: 10.1007/s11357-010-9130-3
PMCID: PMC2861751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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