Article
Homer 2 antagonizes protein degradation in slow-twitch skeletal muscles.
American journal of physiology. Cell physiology - 1 Jan 2013
Bortoloso Elena, Megighian Aram, Furlan Sandra, Gorza Luisa, Volpe Pompeo
Abstract excerpt
Homer represents a new and diversified family of proteins made up of several isoforms. The presence of Homer isoforms, referable to 1b/c and 2a/b, was investigated in fast- and slow-twitch skeletal muscles from both rat and mouse. Homer 1b/c was identical irrespective of the muscle, and Homer 2a/b was instead characteristic of the slow-twitch phenotype. Transition in Homer isoform composition was studied in two...
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