Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions

3 Dec 2020

Abstract excerpt

Muscle atrophy is associated with negative outcomes in a variety of diseases. Identification of a common therapeutic target would address a significant unmet clinical need. Here, we identify a long non-coding RNA (lncRNA) (muscle-atrophy-associated transcript, lncMAAT) as a common regulator of skeletal muscle atrophy. lncMAAT is downregulated in multiple types of muscle-atrophy models both in vivo (denervation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle Physiology and Disorders
Share to RNA Research and Splicing
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33279721
DOI: 10.1016/j.ymthe.2020.12.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory ActionsPMID 33279721Read ↗

An analysis of lncRNA-miRNA-mRNA networks to investigate the effects of HDAC4 inhibition on skeletal muscle atrophy caused by peripheral nerve injurySemantic proximity Read ↗

TNF-α Induced Myotube Atrophy in C2C12 Cell Line Uncovers Putative Inflammatory-Related lncRNAs Mediating Muscle WastingSemantic proximity Read ↗

Long Noncoding RNA lncMUMA Reverses Established Skeletal Muscle Atrophy following Mechanical UnloadingSemantic proximity Read ↗

MicroRNA‑mediated regulation of muscular atrophy: Exploring molecular pathways and therapeutics (Review)Semantic proximity Read ↗

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expressionSemantic proximity Read ↗

Epigenetic control of skeletal muscle atrophySemantic proximity Read ↗

Edward F. Adolph Distinguished Lecture. Skeletal muscle atrophy: Multiple pathways leading to a common outcomeSemantic proximity Read ↗

Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseasesSemantic proximity Read ↗

Molecular Mechanisms of Muscle AtrophySemantic proximity Read ↗

Epigenetics of Skeletal Muscle AtrophySemantic proximity Read ↗

Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophySemantic proximity Read ↗

Transcriptomic Characterisation of the Molecular Mechanisms Induced by RGMa During Skeletal Muscle Hyperplasia and HypertrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.