Article
Polymorphisms of TNF and IL-10 genes and clinical outcome of patients with chronic lymphocytic leukemia.
Genes, chromosomes & cancer - 1 Mar 2013
Lech-Maranda Ewa, Mlynarski Wojciech, Grzybowska-Izydorczyk Olga, Borowiec Maciej, Pastorczak Agata, Cebula-Obrzut Barbara, Klimkiewicz-Wojciechowska Gabriela, Wcislo Monika, Majewski Miroslaw, Kotkowska Aleksandra, Robak Tadeusz, Warzocha Krzysztof
Abstract excerpt
Genetic variations in tumor necrosis factor (TNF) and interleukin-10 (IL-10) were reported to influence susceptibility to and outcome of patients with non-Hodgkin lymphoma. Therefore, we investigated whether single nucleotide polymorphisms in TNF and IL-10 may play a role in the clinical course of patients with chronic lymphocytic leukemia (CLL). TNF-308G>A, IL-10-3575T>A, and IL-10-1082A>G seem to be...
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