Article
Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women.
Cytokine - 1 Oct 2012
Pooja Singh, Chaudhary Preeti, Nayak Lakshma V, Rajender Singh, Saini Karan Singh, Deol Debashish, Kumar Sandeep, Bid Hemant Kumar, Konwar Rituraj
Abstract excerpt
BACKGROUND: Cytokines are known as important regulators of the entire gamut of cancer from initiation, invasion and metastasis. This fact and plethora of gene polymorphism data prompted us to investigate cytokine gene polymorphisms in breast cancer (BC) patients. METHODS: Selected polymorphisms in the IL-1β [-511 T>C (rs16944) and +3954 C>T (rs1143634)]; IL-6 [-174 G>C (rs1800795)]; IL-10 [-1082 A>G (rs1800896),...
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