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Article

The chemokine receptor CXCR7 influences prognosis in human glioma in an IDH1-dependent manner.

Journal of clinical pathology - 1 Oct 2015

Birner Peter, Tchorbanov Andrey, Natchev Sevdalin, Tuettenberg Jochen, Guentchev Marin

Abstract excerpt

AIMS: The chemokine receptor CXCR7 is found on glioma cells and glioma-associated vessels and dependent upon its localisation on tumour or endothelial cells the CXCR7 receptor can mediate glioma cell invasion and tumour angiogenesis. Its expression predicts survival in several types of cancers. METHODS: We immunohistochemically studied the expression of CXCR7 and its ligand SDF1α in a cohort of 354 human patients...

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Source

Identifiers

PMID: 26109200
DOI: 10.1136/jclinpath-2015-202886

Genes

IDH1
PDPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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