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Article

CXCR7 and CXCR4 Expressions in Infiltrative Astrocytomas and Their Interactions with HIF1α Expression and IDH1 Mutation.

Pathology oncology research : POR - 1 Apr 2015

Bianco Andre Macedo, Uno Miyuki, Oba-Shinjo Sueli Mieko, Clara Carlos Afonso, de Almeida Galatro Thais Fernanda, Rosemberg Sergio, Teixeira Manoel Jacobsen, Nagahashi Marie Suely Kazue

Abstract excerpt

The CXCR7, a new receptor for CXCL12 with higher affinity than CXCR4 has raised key issues on glioma cell migration. The aim of this study is to investigate the CXCR7 mRNA expression in diffuse astrocytomas tissues and to evaluate its interactions with CXCR4 and HIF1α expression and IDH1 mutation...

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Source

Identifiers

PMID: 24970694
DOI: 10.1007/s12253-014-9813-7

Genes

CXCR4
IDH1
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24970694-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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