Article
Mutation Analysis for TP53 in Chronic-Type Adult T-Cell Leukemia/Lymphoma.
Journal of clinical and experimental hematopathology : JCEH - 1 Jan 2015
Yoshida Noriaki, Imaizumi Yoshitaka, Utsunomiya Atae, Miyoshi Hiroaki, Arakawa Fumiko, Tsukasaki Kunihiro, Ohshima Koichi, Seto Masao
Abstract excerpt
Adult T-cell leukemia/lymphoma (ATLL) is a T-cell neoplasm caused by human T-cell leukemia virus type I (HTLV-I). ATLL is classified into four clinical subtypes based on the clinical manifestation: acute, lymphoma, chronic and smoldering. Approximately half of chronic type ATLL cases progressed to the acute type. We previously demonstrated that genomic alterations related to the cell cycle de-regulation such as...
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