Article
Role of tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL).
Leukemia - 1 Jun 2002
Hatta Y, Koeffler H P
Abstract excerpt
Adult T cell leukemia/lymphoma (ATLL) is one of the peripheral T cell malignant neoplasms strongly associated with human T cell leukemia virus type-I (HTLV-I). Although the viral transactivating protein Tax has been proposed to play a critical role in leukemogeneis as shown by its transforming activity in various experimental systems, additional cellular events are required for the development of ATLL. One of the...
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