Absence of leukaemic CD 34+ cells in acute myeloid leukaemia is of high prognostic value: a longstanding controversy deciphered

Abstract excerpt

Primary resistance and relapses after initial successful treatment are common in acute myeloid leukaemia and therefore outcome remains poor. More accurate risk group stratification and effective personalized risk adapted treatment are necessary to improve outcome. In the last two decades, controversial results have been published concerning the prognostic relevance of CD34 expression. In this study of 706 acute...

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