Article
The biological characteristics of CD34+ CD2+ adult acute promyelocytic leukemia and the CD34 CD2 hypergranular (M3) and microgranular (M3v) phenotypes.
Haematologica - 1 Mar 2006
Albano Francesco, Mestice Anna, Pannunzio Alessandra, Lanza Francesco, Martino Bruno, Pastore Domenico, Ferrara Felicetto, Carluccio Paola, Nobile Francesco, Castoldi Gianluigi, Liso Vincenzo, Specchia Giorgina
Abstract excerpt
BACKGROUND AND OBJECTIVES: Acute promyelocytic leukemia (APL) is characterized by leukemic cells blocked at the promyelocytic stage of granulocytic differentiation. To date, it is still not clear whether CD34 expression identifies a subset of APL patients with peculiar characteristics. We, therefore, conducted a detailed analysis of CD34 expression at diagnosis in 136 adults with de novo APL. DESIGN AND METHODS:...
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