Article
Fuzzy clustering demonstrates that codon 72 SNP rs1042522 of TP53 gene associated with HNSCC but not with prognoses.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2015
Pinheiro Ugo Borges, Fraga Carlos Alberto de Carvalho, Mendes Danilo Cangussu, Farias Lucyana Conceição, Cardoso Cláudio Marcelo, Silveira Christine Mendes, D'Angelo Marcos Flávio Silveira Vasconcelos, Jones Kimberly Marie, Santos Sérgio Henrique Souza, de Paula Alfredo Maurício Batista, Guimarães André Luiz Sena
Abstract excerpt
It is estimated that 7.6 million people will die as a consequence of head and neck squamous cell carcinoma (HNSCC). Genetic predisposition has emerged as an important risk factor in the development and prognosis of HNSCC. Considering this, the aim of the current study is to assess whether codon 72 SNP of the TP53 gene (rs1042522) is associated with an increased odds ratio of developing HNSCC or with a worse...
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