Article
P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck: a case-control study.
Cancer letters - 26 Sept 2002
Shen Hongbing, Zheng Yuxin, Sturgis Erich M, Spitz Margaret R, Wei Qingyi
Abstract excerpt
p53 plays an important role in cell-cycle control, as it facilitates DNA repair activities in response to DNA damage. An aberrant cell cycle impairs DNA repair and increases the probability of mutations that lead to carcinogenesis. The p53 codon 72 Arg/Pro polymorphism has been suggested to be as...
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