Article
Linkage of TP53 codon 72 pro/pro genotype as predictive factor for nasopharyngeal carcinoma development.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Aug 2006
Sousa Hugo, Santos Alexandra M, Catarino Raquel, Pinto Daniela, Vasconcelos André, Lopes Carlos, Breda Eduardo, Medeiros Rui
Abstract excerpt
Genetic predisposition has been suggested as a cofactor for cancer aetiology and a polymorphism in TP53 codon 72 has been associated as a susceptibility factor for several cancers. Nasopharyngeal carcinoma is a rare neoplasia in western civilizations and genetic predisposition might play an important role in its development. We evaluated the linkage of the polymorphic variants (Arg/Pro) on TP53 codon 72 with...
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