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Article

Genetic Interactions between the Members of the SMN-Gemins Complex in Drosophila.

PloS one - 1 Jan 2015

Borg Rebecca M, Bordonne Rémy, Vassallo Neville, Cauchi Ruben J

Abstract excerpt

The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein. Limiting levels of SMN result in the neuromuscular disorder, spinal muscular atrophy (SMA), which is presently untreatable. The most-documented function of the SMN-Gemins complex concerns the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs). Despite multiple genetic studies, the Gemin proteins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscular Atrophy, Spinal

Share to Ribonucleoproteins, Small Nuclear

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Source

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Identifiers

PMID: 26098872
DOI: 10.1371/journal.pone.0130974
PMCID: PMC4476591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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