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Article

Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.

Biotechnology journal - 1 Jul 2015

Kelly Paul S, Breen Laura, Gallagher Clair, Kelly Shane, Henry Michael, Lao Nga T, Meleady Paula, O'Gorman Donal, Clynes Martin, Barron Niall

Abstract excerpt

microRNA engineering of CHO cells has already proved successful in enhancing various industrially relevant phenotypes and producing various recombinant products. A single miRNA's ability to interact with multiple mRNA targets allows their regulatory capacity to extend to processes such as cellula...

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Identifiers

PMID: 26097147
DOI: 10.1002/biot.201500101

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26097147-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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