Article
Kinetic and functional analysis of abundant microRNAs in extracellular vesicles from normal and stressed cultures of Chinese Hamster Ovary (CHO) cells
2023-06-24
Abstract excerpt
Chinese hamster ovary (CHO) cells release and exchange large quantities of extracellular vesicles (EVs). EVs are highly enriched in microRNAs (miRs, or miRNAs), which are responsible for most of their biological effects. We have recently shown that the miR content of CHO EVs varies significantly under culture stress conditions. Here, we provide a novel stoichiometric (“per-EV”) quantification of miR and protein le...
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Identifiers and source
- Literature Corpus work
- 99881bfe-d05c-52f5-b2e5-43d0c1e7c2fd
- DOI
- 10.1101/2023.06.21.545902
