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Article

Association between interleukin-18 gene polymorphism and Helicobacter pylori infection in the Korean population.

Scientific reports - 22 Jun 2015

Myung Dae-Seong, Lee Wan-Sik, Park Young-Lan, Kim Nuri, Oh Hyung-Hoon, Kim Mi-Young, Oak Chan-Young, Chung Cho-Yun, Park Hyung-Chul, Kim Jong-Sun, Cho Sung-Bum, Kweon Sun-Seog, Joo Young-Eun

Abstract excerpt

Interleukin-18 (IL-18) is a pleiotropic, pro-inflammatory cytokine that is capable of promoting the Th1 response. A predominant Th1 response induces chronic and persistent inflammatory changes in the gastric mucosa in response to Helicobacter pylori (H. pylori) infection. The aim of this study was to investigate the potential association between IL-18 gene polymorphisms and susceptibility to H. pylori infection...

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Identifiers

PMID: 26096341
DOI: 10.1038/srep11535
PMCID: PMC4476145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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