Article
Genetic and environmental influences on total plasma homocysteine and coronary artery disease (CAD) risk among South Indians.
Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2009
Vinukonda Govindaiah, Shaik Mohammad Naushad, Md Nurul Jain Jamal, Prasad Chintakindi Krishna, Rama Devi Akella Radha
Abstract excerpt
BACKGROUND: Hyperhomocysteinemia, a documented risk factor for CAD is highly prevalent in Indians. The rationale behind the current study is to explore the genetic and environmental causes for such high prevalence as there are limited studies in this context. METHODS: A total of 108 CAD cases and 108 controls were analyzed for tHcy and 4 folate pathway genetic polymorphisms [methylene tetrahydrofolate reductase...
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