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Article

Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2000

Chambers J C, Ireland H, Thompson E, Reilly P, Obeid O A, Refsum H, Ueland P, Lane D A, Kooner J S

Abstract excerpt

Plasma homocysteine concentrations are elevated in UK Indian Asians and may contribute to twice as many coronary heart disease (CHD) deaths in this group compared with European whites. The mechanisms underlying elevated homocysteine concentrations among Indian Asians are not well understood. In this study, we have investigated the extent to which the methylenetetrahydrofolate reductase (MTHFR) 677 C-->T mutation...

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Identifiers

PMID: 11073851
DOI: 10.1161/01.atv.20.11.2448

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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