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Article

Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression.

The Journal of pathology - 1 Oct 2015

Randle Suzanne J, Nelson David E, Patel Shachi P, Laman Heike

Abstract excerpt

During the final stages of erythropoiesis, lineage-restricted progenitors mature over three to five cell divisions, culminating with withdrawal from the cell cycle and the loss of most organelles, including mitochondria and nuclei. Recent genome-wide association studies in human populations have associated several SNPs near or within FBXO7 with erythrocyte phenotypes. Fbxo7 encodes a multi-functional F-box...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26095538
DOI: 10.1002/path.4571
PMCID: PMC4583784

Genes

FBXO7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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