Article
Borrelia burgdorferi clinical isolates induce human innate immune responses that are not dependent on genotype.
Immunobiology - 1 Oct 2015
Mason Lauren M K, Herkes Eduard A, Krupna-Gaylord Michelle A, Oei Anneke, van der Poll Tom, Wormser Gary P, Schwartz Ira, Petzke Mary M, Hovius Joppe W R
Abstract excerpt
Borrelia burgdorferi can be categorized based on restriction fragment length polymorphism analysis into ribosomal spacer type (RST) 1, 2 and 3. A correlation between RST type and invasiveness of Borrelia isolates has been demonstrated in clinical studies and experimental models, and RST 1 isolates are more likely to cause disseminated disease than RST 3 isolates. We hypothesized that this could partially be due...
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