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Article

The propensity of different Borrelia burgdorferi sensu stricto genotypes to cause disseminated infections in humans.

The American journal of tropical medicine and hygiene - 1 May 2008

Dykhuizen Daniel E, Brisson Dustin, Sandigursky Sabina, Wormser Gary P, Nowakowski John, Nadelman Robert B, Schwartz Ira

Abstract excerpt

Lineages of Borrelia burgdorferi, the bacterium that causes Lyme disease, can be characterized by distinct alleles at the outer surface protein C (ospC) locus. The lineages marked by ospC genotypes have been shown to be differentially invasive in different species of mammals, including humans; genotypes A, B, I, and K effectively disseminate to human blood and cerebrospinal fluid. In this report, we extend the...

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PMID: 18458317
PMCID: PMC2387051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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