Article
Association between human leukocyte antigen class II alleles and genotype of Borrelia burgdorferi in patients with early lyme disease.
The Journal of infectious diseases - 1 Dec 2005
Wormser Gary P, Kaslow Richard, Tang Jianming, Wade Karen, Liveris Dionysios, Schwartz Ira, Klempner Mark
Abstract excerpt
BACKGROUND: On the basis of a polymerase chain reaction-restriction fragment-length polymorphism analysis of the 16S-23S ribosomal DNA intergenic spacer, clinical isolates of Borrelia burgdorferi can be classified into 3 genotypes designated as RST1, RST2, and RST3. RST1 strains are the most pathogenic, and RST3 strains are the least pathogenic. METHODS: Human leukocyte antigen (HLA) class II alleles were...
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