Article
Trans-Species Polymorphism in Immune Genes: General Pattern or MHC-Restricted Phenomenon?
Journal of immunology research - 1 Jan 2015
Těšický Martin, Vinkler Michal
Abstract excerpt
Immunity exhibits extraordinarily high levels of variation. Evolution of the immune system in response to host-pathogen interactions in particular ecological contexts appears to be frequently associated with diversifying selection increasing the genetic variability. Many studies have documented that immunologically relevant polymorphism observed today may be tens of millions years old and may predate the...
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