Article
Analysis of transcriptional control mechanisms of capsule expression in Neisseria meningitidis.
International journal of medical microbiology : IJMM - 1 Nov 2001
Von Loewenich F D, Wintermeyer E, Dümig M, Frosch M
Abstract excerpt
The major virulence factor which contributes to the survival of Neisseria meningitidis in the blood stream and the cerebrospinal fluid is the capsular polysaccharide. Expression of the capsule genes of N. meningitidis serogroups B, C, W-135 and Y is controlled by an intergenic region separating the capsule biosynthesis operon (siaA-D) and the capsule transport operon (ctrA-D). To further investigate capsule...
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