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Expansion and long-term culture of human spermatogonial stem cells via the activation of SMAD3 and AKT pathways

18 Jun 2015

Abstract excerpt

Spermatogonial stem cells (SSCs) can differentiate into spermatids, reflecting that they could be used in reproductive medicine for treating male infertility. SSCs are able to become embryonic stem-like cells with the potentials of differentiating into numerous cell types of the three germ layers and they can transdifferentiate to mature and functional cells of other lineages, highlighting significant...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 26088866
DOI: 10.1177/1535370215590822

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