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Long-term Culture of Human SSEA-4 Positive Spermatogonial Stem Cells (SSCs)

1 Jan 2011

Abstract excerpt

culture of isolated human SSCs. Here using SSEA-4 as an optimal marker for isolation of a subpopulation of SSCs, we show that SSEA-4 positive cells express the highest level of SSC genes compared to other subpopulations isolated with different markers, and can be maintained in culture for over 14 passages which we were unable to obtain with other SSCs markers including GPR125 and ITGA6. In addition, we have...

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PMID: 24466499
DOI: 10.4172/2157-7633.s2-003

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