Article
Isolation, characterization, and culture of human spermatogonia.
Biology of reproduction - 1 Feb 2010
He Zuping, Kokkinaki Maria, Jiang Jiji, Dobrinski Ina, Dym Martin
Abstract excerpt
This study was designed to isolate, characterize, and culture human spermatogonia. Using immunohistochemistry on tubule sections, we localized GPR125 to the plasma membrane of a subset of the spermatogonia. Immunohistochemistry also showed that MAGEA4 was expressed in all spermatogonia (A(dark), A(pale), and type B) and possibly preleptotene spermatocytes. Notably, KIT was expressed in late spermatocytes and...
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