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Recent advances in isolation, identification, and culture of mammalian spermatogonial stem cells

12 Jun 2021

Abstract excerpt

Continuous spermatogenesis depends on the self-renewal and differentiation of spermatogonial stem cells (SSCs). SSCs, the only male reproductive stem cells that transmit genetic material to subsequent generations, possess an inherent self-renewal ability, which allows the maintenance of a steady stem cell pool. SSCs eventually differentiate to produce sperm. However, in an in vitro culture system, SSCs can be...

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PMID: 34135169
DOI: 10.4103/aja.aja_41_21

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