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Evaluation of candidate spermatogonial markers <scp>ID</scp>4 and <scp>GPR</scp>125 in testes of adult human cadaveric organ donors

5 Jun 2014

Abstract excerpt

The optimal markers for human spermatogonial stem cells (SSCs) are not known. Among the genes recently linked to SSCs in mice and other animals are the basic helix-loop-helix transcription factor ID4 and the orphan G-protein-coupled receptor GPR125. While ID4 and GPR125 are considered putative markers for SSCs, they have not been evaluated for coexpression in human tissue. Furthermore, neither the size nor the...

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PMID: 24902969
DOI: 10.1111/j.2047-2927.2014.00226.x

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