Article
DNA repair gene XRCC1 and XRCC4 variations and risk of endometriosis: an association study.
Gynecologic and obstetric investigation - 1 Jan 2015
Saliminejad Kioomars, Saket Mitra, Kamali Koorosh, Memariani Toktam, Khorram Khorshid Hamid Reza
Abstract excerpt
BACKGROUND: Endometriosis is a polygenic and multifactorial disease. DNA damage plays a major role in mutagenesis, carcinogenesis and aging and is usually repaired by the action of several DNA repair enzymes. We investigated the association of the common variations of the DNA repair genes XRCC1 and XRCC4 with susceptibility to endometriosis in an Iranian population. METHODS: In total, 160 patients with...
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