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Article

Association of XRCC4 and XRCC5 gene polymorphisms with polycystic ovarian syndrome in an Indian cohort.

Personalized medicine - 1 Feb 2026

Sridhar Nikitha, Venkatakrishnan Gayathri, Benjamin Jiby Jolly, Ramaswamy Padmavathi, Baijumon Bindhu Sabari Krishnan, Antony Sharon Benita, Tholath Rahul Rajan Mathews, Koshy Teena

Abstract excerpt

AIM: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in Indian women, with prevalence influenced by ethnicity, lifestyle, and associated metabolic conditions. Given the emerging link between genomic instability and PCOS, this study aimed to assess the association of polymorphisms in two DNA repair genes, XRCC4 rs28360071 and XRCC5 rs6147172, with PCOS susceptibility in an Indian cohort. METHODS: A...

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Identifiers

PMID: 41728861
DOI: 10.1080/17410541.2026.2634607

Genes

XRCC4
XRCC5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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