Article
XRCC4 codon 247*A and XRCC4 promoter -1394*T related genotypes but not XRCC4 intron 3 gene polymorphism are associated with higher susceptibility for endometriosis.
Molecular reproduction and development - 1 May 2008
Hsieh Yao-Yuan, Bau Da-Tian, Chang Chi-Chen, Tsai Chang-Hai, Chen Chih-Ping, Tsai Fuu-Jen
Abstract excerpt
DNA repair systems act to maintain genome integrity in the face of replication errors, environmental insults, and the cumulative effects of age. Genetic variants in DNA repair genes such as X-ray repair cross-complementing group 4 (XRCC4) might influence the ability to repair damaged DNA. Herein we aimed to investigate whether some XRCC4-related polymorphisms were associated with endometriosis susceptibility....
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