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Article

A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies.

Medicine - 17 Dec 2021

Zhang Xue Qin, Li Li

Abstract excerpt

BACKGROUND: Gynecological malignant tumor is a serious threat to women's health, cervical cancer, endometrial cancer and ovarian cancer are the most common. The eponymous protein encoded by the XRCC1 (X-ray repair cross complementation 1) gene is an important functional protein in the process of single-stranded DNA damage. Non-synonymous mutations of XRCC1 gene cause amino acid sequence changes that affect...

Topics

Case-Control Studies
DNA-Binding Proteins
Endometrial Neoplasms
Female
Genetic Predisposition to Disease
Humans
Polymorphism, Single Nucleotide
Risk Factors
Uterine Cervical Neoplasms
X-ray Repair Cross Complementing Protein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34918657
DOI: 10.1097/MD.0000000000028030
PMCID: PMC8677953

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