Article
Aggregate blood pressure responses to serial dietary sodium and potassium intervention: defining responses using independent component analysis.
BMC genetics - 20 Jun 2015
Chen Gengsheng, de las Fuentes Lisa, Gu Chi C, He Jiang, Gu Dongfeng, Kelly Tanika, Hixson James, Jacquish Cashell, Rao D C, Rice Treva K
Abstract excerpt
BACKGROUND: Hypertension is a complex trait that often co-occurs with other conditions such as obesity and is affected by genetic and environmental factors. Aggregate indices such as principal components among these variables and their responses to environmental interventions may represent novel information that is potentially useful for genetic studies. RESULTS: In this study of families participating in the...
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