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Article

NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?

18 Jun 2015

Abstract excerpt

Aging was recently described as a life event programmed by the hypothalamus, a key brain region that is crucial for the neuroendocrine interaction between the central nervous system and the periphery. Autophagy impairment is a hallmark of aging, contributing to the aging phenotype and to the aggravation of age-related diseases. Since hypothalamic autophagy decreases with age, strategies to promote autophagy in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26086271
DOI: 10.1080/15548627.2015.1062202

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