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Article

M(o)TOR of aging: MTOR as a universal molecular hypothalamus

16 Jul 2013

Abstract excerpt

A recent ground-breaking publication described hypothalamus-driven programmatic aging. As a Russian proverb goes "everything new is well-forgotten old". In 1958, Dilman proposed that aging and its related diseases are programmed by the hypothalamus. This theory, supported by beautiful experiments, remained unnoticed just to be re-discovered recently. Yet, it does not explain all manifestations of aging. And would...

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PMID: 23872658
DOI: 10.18632/aging.100580

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