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Article

TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases.

American journal of physiology. Renal physiology - 1 Sept 2015

Ilatovskaya Daria V, Staruschenko Alexander

Abstract excerpt

Podocytes (terminally differentiated epithelial cells of the glomeruli) play a key role in the maintenance of glomerular structure and permeability and in the incipiency of various renal abnormalities. Injury to podocytes is considered a major contributor to the development of kidney disease as their loss causes proteinuria and progressive glomerulosclerosis. The physiological function of podocytes is critically...

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Source

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Identifiers

PMID: 26084930
DOI: 10.1152/ajprenal.00186.2015
PMCID: PMC4556891

Genes

TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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