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Article

A Putative Role for TRPC6 in Immune-Mediated Kidney Injury

16 Nov 2023

Abstract excerpt

Excessive activation of the immune system is the cause of a wide variety of renal diseases. However, the pathogenic mechanisms underlying the aberrant activation of the immune system in the kidneys often remain unknown. TRPC6, a member of the Ca2+-permeant family of TRPC channels, is important in glomerular epithelial cells or podocytes for the process of glomerular filtration. In addition, TRPC6 plays a crucial...

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PMID: 38003608
DOI: 10.3390/ijms242216419

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