Article
TRPC6 - a new podocyte gene involved in focal segmental glomerulosclerosis.
Trends in molecular medicine - 1 Dec 2005
Kriz Wilhelm
Abstract excerpt
Hereditary kidney diseases have long been an enigma with respect to the identity of the mutated genes and the mechanisms by which they develop. Recently, the podocyte has been identified as a primary target in both genetic and acquired glomerular disorders. Mutations discovered by Winn et al. and Reiser et al. in the gene encoding TRPC6, a non-selective cation channel of the TRP family expressed in podocyte foot...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
