Article
CRY1 circadian gene variant interacts with carbohydrate intake for insulin resistance in two independent populations: Mediterranean and North American.
Chronobiology international - 1 Jun 2014
Dashti Hassan S, Smith Caren E, Lee Yu-Chi, Parnell Laurence D, Lai Chao-Qiang, Arnett Donna K, Ordovás José M, Garaulet Marta
Abstract excerpt
Dysregulation in the circadian system induced by variants of clock genes has been associated with type 2 diabetes. Evidence for the role of cryptochromes, core components of the system, in regulating glucose homeostasis is not supported by CRY1 candidate gene association studies for diabetes and insulin resistance in human, suggesting possible dietary influences. The purpose of this study was to test for...
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