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Investigating the relationships between unfavorable sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

2020-09-01

Abstract excerpt

<h4>Background</h4> Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined adjusted multivariable regression (AMV) and MR analyses of phenotypes of unfavourable sleep on 113 metabolomic traits to investigate possible biochemical mechanisms linking s...

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Literature Corpus work
4dc1b040-a476-5b4e-9002-dd53f183aea8
DOI
10.1101/2020.08.27.20173518
Open publication

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Investigating the relationships between unfavorable sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analysesDOI 10.1101/2020.08.27.20173518
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