Article
Association of Canonical Wnt/β-Catenin Pathway and Type 2 Diabetes: Genetic Epidemiological Study in Han Chinese.
Nutrients - 15 Jun 2015
Wang Jinjin, Zhao Jingzhi, Zhang Jianfeng, Luo Xinping, Gao Kaiping, Zhang Ming, Li Linlin, Wang Chongjian, Hu Dongsheng
Abstract excerpt
We aimed to investigate the associations of polymorphisms in Canonical Wnt/β-catenin pathway (WNT) signaling genes (including low-density lipoprotein-related protein 5 [LRP5] and transcription factor 7-like 2 [TCF7L2] gene) and the downstream gene glucagon (GCG) and risk of type 2 diabetes mellitus (T2DM) in a Han Chinese population. We genotyped the single nucleotide polymorphisms (SNPs) for LRP5, TCF7L2 and GCG...
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