Article
Association between Low-density Lipoprotein Receptor-related Protein 5 Polymorphisms and Type 2 Diabetes Mellitus in Han Chinese: a Case-control Study.
Biomedical and environmental sciences : BES - 1 Jul 2015
You Hai Fei, Zhao Jing Zhi, Zhai Yu Jia, Yin Lei, Pang Chao, Luo Xin Ping, Zhang Ming, Wang Jin Jin, Li Lin Lin, Wang Yan, Wang Qian, Wang Bing Yuan, Ren Yong Cheng, Hu Dong Sheng
Abstract excerpt
OBJECTIVE: To investigate the association between low-density lipoprotein receptor-related protein 5 (LRP5) variants (rs12363572 and rs4930588) and type 2 diabetes mellitus (T2DM) in Han Chinese. METHODS: A total of 1842 T2DM cases (507 newly diagnosed cases and 1335 previously diagnosed cases) and 7777 controls were included in this case-control study. PCR-RFLP was conducted to detect the genotype of the two...
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